Motif ID: HOX{A5,B5}.p2

Z-value: 2.028


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA5chr7_-_271832250.243.7e-04Click!
HOXB5chr17_-_466710430.153.1e-02Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_9268513 56.281 A2M
alpha-2-macroglobulin
chr2_+_17721806 44.208 NM_003385
VSNL1
visinin-like 1
chr12_-_6798419 39.566 ZNF384
zinc finger protein 384
chr20_+_44650260 36.780 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_+_17721983 35.949 VSNL1
visinin-like 1
chr11_-_111782447 33.337 NM_001885
CRYAB
crystallin, alpha B
chr12_-_91572328 31.445 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr1_-_163113129 30.059 RGS5
regulator of G-protein signaling 5
chrM_+_12283 25.465


chr6_+_121756744 24.501 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr19_-_53757940 23.779 ZNF677
zinc finger protein 677
chr12_-_6798528 21.328 NM_133476
ZNF384
zinc finger protein 384
chr5_+_17217474 21.201 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr3_+_115342302 20.998 GAP43
growth associated protein 43
chrX_+_135230736 20.987 NM_001159700
FHL1
four and a half LIM domains 1
chr1_-_183274008 20.723 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_184723952 20.455 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr11_-_62472901 19.570


chr13_-_45048436 19.088 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr12_+_54955226 18.985 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chrX_+_100333835 18.009 NM_021637
TMEM35
transmembrane protein 35
chr6_-_31981049 17.925 NM_032470
TNXB
tenascin XB
chr12_-_56101465 17.842 ITGA7
integrin, alpha 7
chr9_-_86571652 17.071 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr11_-_35440514 16.441 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_-_170043608 16.224 NM_001204514
NM_001204516
NM_014970
KIFAP3


kinesin-associated protein 3


chr3_+_11034436 16.208 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr19_-_49944613 16.103 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr16_-_31085503 15.635 NM_024706
ZNF668
zinc finger protein 668
chr9_+_130374466 15.301 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr8_+_21916858 14.927 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr14_-_23834417 14.864 EFS
embryonal Fyn-associated substrate
chr1_+_160085519 14.629 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr2_-_220173693 14.574 NM_001199764
PTPRN
protein tyrosine phosphatase, receptor type, N
chr6_+_31868775 14.543 NM_001178063
C2
complement component 2
chrX_-_107225588 14.476 NM_031273
TEX13B
testis expressed 13B
chr5_-_149535138 14.423 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr19_-_14064192 14.340 NM_001146254
NM_001146255
PODNL1

podocan-like 1

chr12_-_9268522 13.894 NM_000014
A2M
alpha-2-macroglobulin
chr1_-_12677347 13.811 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_169337193 13.561 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr3_-_183543295 13.391 NM_024871
MAP6D1
MAP6 domain containing 1
chr20_-_23618382 13.167 NM_000099
CST3
cystatin C
chr11_+_17757494 13.164 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr8_+_21916685 12.804 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr19_+_8117887 12.742 CCL25
chemokine (C-C motif) ligand 25
chr19_-_50266514 12.710 NM_021733
TSKS
testis-specific serine kinase substrate
chr3_-_51993955 12.467 PCBP4
poly(rC) binding protein 4
chr12_-_9268475 12.384 A2M
alpha-2-macroglobulin
chr17_-_17140492 12.365 NM_144606
NM_144997
FLCN

folliculin

chr1_+_203020310 12.264 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr3_+_11034419 12.139 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_+_156589085 12.112 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr22_+_31031672 11.999 NM_001001479
SLC35E4
solute carrier family 35, member E4
chr20_-_44455932 11.924 NM_003279
TNNC2
troponin C type 2 (fast)
chr11_-_57004674 11.856 NM_005161
APLNR
apelin receptor
chr19_+_47759802 11.719 CCDC9
coiled-coil domain containing 9
chr12_+_108909049 11.527 NM_007076
FICD
FIC domain containing
chr16_+_12070501 11.370 NM_032167
SNX29
sorting nexin 29
chr19_+_47759730 11.357 NM_015603
CCDC9
coiled-coil domain containing 9
chr19_+_54057898 11.209 NM_001253801
ZNF331
zinc finger protein 331
chr13_-_46626845 11.135 NM_015070
ZC3H13
zinc finger CCCH-type containing 13
chr17_+_39845142 11.043 EIF1
eukaryotic translation initiation factor 1
chr12_-_106533810 10.983 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr12_+_7282963 10.966 NM_014718
CLSTN3
calsyntenin 3
chr12_-_16759939 10.859 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_-_62975005 10.790 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr6_-_31514620 10.763 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr17_-_5404304 10.752 NM_001162371
LOC728392
uncharacterized LOC728392
chr9_+_42717233 10.731 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr14_-_23822025 10.666 NM_016609
SLC22A17
solute carrier family 22, member 17
chr17_-_41984888 10.550 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr9_+_137967401 10.544 OLFM1
olfactomedin 1
chr2_+_113816214 10.243 NM_173170
IL36RN
interleukin 36 receptor antagonist
chr10_+_114136014 10.207 ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_-_9268440 10.106 A2M
alpha-2-macroglobulin
chr16_+_30418885 10.086 ZNF771
zinc finger protein 771
chr6_-_31782786 10.075 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr17_+_7284292 9.892 NM_001251902
NM_003985
TNK1

tyrosine kinase, non-receptor, 1

chr4_-_176733413 9.792 GPM6A
glycoprotein M6A
chr17_+_7623038 9.732 NM_020877
DNAH2
dynein, axonemal, heavy chain 2
chr19_+_7694658 9.693 NM_001171155
C19orf79
chromosome 19 open reading frame 79
chr8_-_143999255 9.680 NM_000498
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr1_-_203320249 9.622


chr3_+_49027281 9.576 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr2_-_217540722 9.570 IGFBP5
insulin-like growth factor binding protein 5
chr13_-_46679143 9.542 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chrX_-_62974987 9.509 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_4488707 9.484 NM_020638
FGF23
fibroblast growth factor 23
chr19_-_17958814 9.422 NM_000215
JAK3
Janus kinase 3
chr6_-_29600959 9.374 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr9_-_34710062 9.245 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr9_-_70429730 9.239 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr1_+_203444955 9.216 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr19_+_41515495 9.054 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr12_+_7167979 8.937 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr3_-_133648517 8.896 NM_025041
C3orf36
chromosome 3 open reading frame 36
chr3_-_127541160 8.891 NM_007283
MGLL
monoglyceride lipase
chr13_-_25496913 8.863 CENPJ
centromere protein J
chr13_+_58205943 8.824 PCDH17
protocadherin 17
chr3_+_39509069 8.766 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr1_+_4714668 8.689 AJAP1
adherens junctions associated protein 1
chr20_+_3024267 8.603 NM_001501
NM_178331
NM_178332
GNRH2


gonadotropin-releasing hormone 2


chr12_+_7013896 8.571 NM_001135217
NM_006992
NM_201650
LRRC23


leucine rich repeat containing 23


chr6_+_31082526 8.559 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_-_41985112 8.541 NM_005374
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr3_-_42917632 8.526 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr11_-_57283145 8.520 NM_003627
SLC43A1
solute carrier family 43, member 1
chr3_-_46506342 8.438 NM_002343
LTF
lactotransferrin
chr11_-_117102810 8.424 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr11_-_114271052 8.364 NM_019021
C11orf71
chromosome 11 open reading frame 71
chr14_-_23834378 8.345 EFS
embryonal Fyn-associated substrate
chr15_+_43809805 8.305 NM_002373
MAP1A
microtubule-associated protein 1A
chr16_-_49860917 8.240 NM_015069
ZNF423
zinc finger protein 423
chr22_-_27013959 8.212 NM_001887
CRYBB1
crystallin, beta B1
chr19_+_57999078 7.995 NM_001098491
NM_001098492
NM_001098493
NM_001098494
NM_001098495
NM_001098496
NM_024691
ZNF419






zinc finger protein 419






chr1_+_205236591 7.969 TMCC2
transmembrane and coiled-coil domain family 2
chr16_-_71610948 7.928 NM_000353
TAT
tyrosine aminotransferase
chr4_+_41258909 7.879 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_10490774 7.847 NM_001243768
APITD1-CORT
APITD1-CORT readthrough
chr1_+_114522029 7.780 NM_020190
OLFML3
olfactomedin-like 3
chr1_+_220701800 7.772 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_-_120935893 7.748 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr1_-_23810627 7.743 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr13_-_25497054 7.735 NM_018451
CENPJ
centromere protein J
chr10_+_50817140 7.667 NM_020984
CHAT
choline O-acetyltransferase
chr16_+_30968614 7.585 NM_014712
SETD1A
SET domain containing 1A
chr5_+_149569519 7.576 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr14_+_76618272 7.564 C14orf118
chromosome 14 open reading frame 118
chr16_+_86544104 7.507 NM_001451
FOXF1
forkhead box F1
chrX_+_8432870 7.477 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr19_-_8642232 7.469 MYO1F
myosin IF
chr10_+_114135937 7.454 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_+_50497790 7.426 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr9_-_70178814 7.385 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr9_+_137967088 7.331 NM_014279
NM_006334
OLFM1

olfactomedin 1

chr16_-_67427335 7.312 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr4_-_114900802 7.276 NM_024590
ARSJ
arylsulfatase family, member J
chr9_+_137967366 7.260 OLFM1
olfactomedin 1
chr4_+_55523906 7.254 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr12_-_6798619 7.238 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chrX_-_6453158 7.228 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr6_+_31588524 7.191 PRRC2A
proline-rich coiled-coil 2A
chr9_+_27109138 7.154 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr17_-_8063946 7.135 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr10_+_114135965 7.079 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_29600859 6.922 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_125550674 6.868 NM_001612
NM_020069
NM_020107
NM_020108
ACRV1



acrosomal vesicle protein 1



chrY_-_1281526 6.835 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr1_+_46806389 6.832 NM_199044
NSUN4
NOP2/Sun domain family, member 4
chr19_+_8274179 6.798 NM_024552
CERS4
ceramide synthase 4
chr9_-_4741798 6.752 NM_001199855
AK3
adenylate kinase 3
chr9_-_34620499 6.749 DCTN3
dynactin 3 (p22)
chr4_+_41258895 6.738 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr19_+_50529276 6.702 ZNF473
zinc finger protein 473
chr1_+_202317798 6.701 NM_001167857
NM_001167858
NM_002481
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr9_-_135819995 6.597 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr3_-_164914448 6.408 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr16_-_89556886 6.398 NM_013275
ANKRD11
ankyrin repeat domain 11
chrX_-_137949716 6.394 NM_001139502
FGF13
fibroblast growth factor 13
chr2_+_113816684 6.391 NM_012275
IL36RN
interleukin 36 receptor antagonist
chr4_-_76944585 6.364 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr20_-_1638359 6.349 NM_001039508
NM_018556
NM_080816
SIRPG


signal-regulatory protein gamma


chr22_-_36556781 6.336 NM_145640
APOL3
apolipoprotein L, 3
chr14_+_76618289 6.303 C14orf118
chromosome 14 open reading frame 118
chr6_-_29595746 6.282 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_184723996 6.275 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr11_-_117102758 6.270 PCSK7
proprotein convertase subtilisin/kexin type 7
chr4_-_57687827 6.250 NM_021114
SPINK2
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
chr14_+_76618244 6.233 NM_017926
NM_017972
C14orf118

chromosome 14 open reading frame 118

chr7_+_90225607 6.221 CDK14
cyclin-dependent kinase 14
chr3_-_109056388 6.183 NM_018189
DPPA4
developmental pluripotency associated 4
chr10_+_115310589 6.155 NM_001177660
HABP2
hyaluronan binding protein 2
chr5_+_148520985 6.151 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr17_+_20771745 6.146


chr3_-_14989399 6.134 LOC100505641
uncharacterized LOC100505641
chr6_-_46922533 6.132 NM_015234
GPR116
G protein-coupled receptor 116
chr9_-_4742042 6.127 NM_001199853
AK3
adenylate kinase 3
chr16_-_2390711 6.093 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr13_+_58205788 6.091 NM_001040429
PCDH17
protocadherin 17
chrX_+_57618440 6.086 ZXDB
zinc finger, X-linked, duplicated B
chr11_+_74862031 6.082 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chrX_-_104465349 6.036 NM_031274
TEX13A
testis expressed 13A
chr1_-_203154304 6.035 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_156435670 6.034 NM_001184997
RNF32
ring finger protein 32
chrX_-_130423387 6.024 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr4_+_41258941 6.008 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr15_-_26108869 5.942 ATP10A
ATPase, class V, type 10A
chr1_+_203734283 5.926 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr11_+_62475165 5.852 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr16_+_57769626 5.793 NM_005886
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr4_-_48014960 5.777 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr8_-_66701175 5.774 NM_002603
PDE7A
phosphodiesterase 7A
chr20_-_56100138 5.750 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr5_+_161274939 5.711 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_26371461 5.686 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr3_-_109056333 5.684 DPPA4
developmental pluripotency associated 4
chr16_-_58005011 5.605 NM_001135639
NM_001297
CNGB1

cyclic nucleotide gated channel beta 1

chr12_-_8218930 5.561 NM_004054
C3AR1
complement component 3a receptor 1
chr6_+_31554975 5.523 NM_001166538
NM_007161
NM_205840
LST1


leukocyte specific transcript 1



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 5.98e-11 GO:0065007 biological regulation
1.33 1.11e-08 GO:0050896 response to stimulus
1.45 1.00e-07 GO:0023052 signaling
1.26 4.78e-07 GO:0050789 regulation of biological process
1.58 4.63e-06 GO:0065008 regulation of biological quality
1.32 5.39e-06 GO:0032501 multicellular organismal process
1.93 1.34e-05 GO:0009611 response to wounding
1.24 2.37e-05 GO:0050794 regulation of cellular process
1.35 4.96e-05 GO:0051716 cellular response to stimulus
2.71 5.22e-05 GO:0006954 inflammatory response
1.52 5.92e-05 GO:0042221 response to chemical stimulus
1.92 9.21e-05 GO:0006952 defense response
1.38 2.44e-04 GO:0007165 signal transduction
1.77 4.58e-04 GO:0007154 cell communication
1.53 9.23e-04 GO:0007166 cell surface receptor linked signaling pathway
14.20 1.23e-03 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
1.79 1.26e-03 GO:0006811 ion transport
1.44 1.68e-03 GO:0006950 response to stress
2.07 2.66e-03 GO:0019226 transmission of nerve impulse
2.07 2.66e-03 GO:0035637 multicellular organismal signaling
12.62 3.51e-03 GO:0048880 sensory system development
12.62 3.51e-03 GO:0048892 lateral line nerve development
12.62 3.51e-03 GO:0048895 lateral line nerve glial cell differentiation
12.62 3.51e-03 GO:0048925 lateral line system development
12.62 3.51e-03 GO:0048937 lateral line nerve glial cell development
12.62 3.51e-03 GO:0050935 iridophore differentiation
1.82 4.11e-03 GO:0007267 cell-cell signaling
1.31 4.96e-03 GO:0032502 developmental process
1.33 6.15e-03 GO:0051179 localization
6.82 6.61e-03 GO:0001755 neural crest cell migration
1.37 8.07e-03 GO:0048731 system development
1.32 1.11e-02 GO:0007275 multicellular organismal development
8.84 1.12e-02 GO:0048485 sympathetic nervous system development
2.04 1.74e-02 GO:0007268 synaptic transmission
10.33 1.76e-02 GO:0060600 dichotomous subdivision of an epithelial terminal unit
1.32 2.87e-02 GO:0048856 anatomical structure development
1.44 3.20e-02 GO:0048583 regulation of response to stimulus
9.47 3.37e-02 GO:0048846 axon extension involved in axon guidance
9.47 3.37e-02 GO:0090184 positive regulation of kidney development
1.11 3.48e-02 GO:0009987 cellular process
1.35 3.85e-02 GO:0048518 positive regulation of biological process
1.88 3.99e-02 GO:0051336 regulation of hydrolase activity
1.50 4.36e-02 GO:0065009 regulation of molecular function

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.68 2.13e-10 GO:0044459 plasma membrane part
1.88 9.70e-09 GO:0005887 integral to plasma membrane
1.86 1.50e-08 GO:0031226 intrinsic to plasma membrane
1.61 1.54e-07 GO:0005576 extracellular region
1.29 8.20e-04 GO:0005886 plasma membrane
1.29 8.93e-04 GO:0071944 cell periphery
2.10 1.38e-03 GO:0045202 synapse
1.73 2.83e-03 GO:0005615 extracellular space
1.60 5.55e-03 GO:0044421 extracellular region part
2.37 1.51e-02 GO:0034702 ion channel complex
4.17 1.73e-02 GO:0044309 neuron spine
1.94 1.80e-02 GO:0044463 cell projection part
2.45 3.43e-02 GO:0043025 neuronal cell body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.80 3.85e-03 GO:0043565 sequence-specific DNA binding
1.64 7.07e-03 GO:0022857 transmembrane transporter activity
1.99 9.51e-03 GO:0015267 channel activity
1.99 1.01e-02 GO:0022803 passive transmembrane transporter activity
10.52 2.33e-02 GO:0005283 sodium:amino acid symporter activity
1.91 4.87e-02 GO:0022838 substrate-specific channel activity